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Disclosures: Hyunseok Kim: Nothing to Disclose, Ally Hatcher: Nothing to Disclose, Vikrant Rachakonda: Nothing to Disclose, Linda Azab: Nothing to Disclose, Touseef Qureshi: Nothing to Disclose, Lixia Wang: Nothing to Disclose, Ji Hye Min: Nothing to Disclose, Polly Kirsch: Nothing to Disclose, Yee Hui Yeo: Nothing to Disclose, Walid Ayoub: Intercept: Speaking and Teaching, Mirum: Grant/Research Support, GSK: Consultant, GSK: Grant/Research Support, Madrigal: Grant/Research Support, Cymabay: Consultant, Ipsen: Grant/Research Support, Zydus: Grant/Research Support, Alexander Kuo: Nothing to Disclose, Hirsh Trivedi: Nothing to Disclose, Aarshi Vipani: Nothing to Disclose, Yun Wang: Nothing to Disclose, Stephen Pandol: Nothing to Disclose, Ju Dong Yang: Nothing to Disclose, Shelly Lu: Nothing to Disclose, Debiao Li: Nothing to Disclose 1587 HEPATOCYTE-SPECIFIC DELETION OF BETAINE HOMOCYSTEINE METHYLTRANSFERASE PROMOTES AGE-DEPENDENT PROGRESSION OF LIVER DISEASE Poonam Sagar 1 Sathish Perumal 1 Ramachandran Rajamanickam 1 Natalia Osna 1 Karuna Rasineni 1 Kusum Kharbanda 2 , 1 University of Nebraska Medical Center, 2 Department of Veterans Affairs, Veterans Affairs Nebraska-Western Iowa Health Care System Background: Betaine homocysteine methyltransferase (BHMT), an enzyme involved in one-carbon metabolism, plays a critical role in maintaining liver health
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S -glutathionylation controls numerous physiological processes, such as cellular growth and differentiation, cell cycle progression, transcriptional activity, cytoskeletal function, cellular metabolism, and apoptosis (Klatt and Lamas, 2000
Trigger Point Injection Trigger point injections can be used to treat pain from a number of conditions including fibromyalgia, tension headache, and myofascial pain syndrome
